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Dietary restriction (DR), the practice of reducing nutrient intake without inducing malnutrition, has long been linked to extended lifespan. While various methods like caloric restriction, nutrient composition alteration, and intermittent fasting have been explored, compliance challenges and unresolved mechanisms often complicate their implementation. Recent research, however, has uncovered a more...
The origins of human migration into ancient Sicily hold profound implications for understanding how early Homo sapiens colonized Mediterranean islands. New archaeological discoveries and methods have illuminated paths taken by early communities, reshaping theories about migration patterns and environmental adaptation during the Late Pleistocene. Recent studies suggest that Sicily, located...
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously called non-alcoholic fatty liver disease, is a widespread health issue impacting about 25% of the global population. A more severe form, metabolic dysfunction-associated steatohepatitis (MASH), can lead to cirrhosis—a life-threatening condition characterized by advanced liver fibrosis. Understanding and addressing the underlying causes of...
