As per DelveInsight’s assessment, globally, about 15+ key pharma and biotech companies are working on 15+ pipeline drugs in the Chondrosarcoma therapeutics landscape based on different Routes of Administration (ROA), Mechanism of Action (MOA), and molecule types. Several of the therapies are in the advanced stages of clinical development and are expected to launch in the coming years.
Key highlights of the Chondrosarcoma pipeline insights report:
Novel therapies targeting IDH mutations have the potential to make a significant impact in the chondrosarcoma treatment landscape, capturing a substantial share of the untapped market, given that nearly 65% of chondrosarcoma cases are linked to IDH mutations.
According to the updated NCCN guidelines, ivosidenib has now been included as a treatment option for patients with IDH1-mutant conventional or dedifferentiated chondrosarcoma.
Additionally, the ESMO 2021 clinical practice guidelines for diagnosis, treatment, and follow-up suggest that trabectedin could be considered as a treatment option for mesenchymal chondrosarcoma.
INBRX-109, one of the leading candidates in the emerging treatment landscape, shows promise as a new therapeutic option for patients with unresectable conventional chondrosarcoma, offering the potential to extend progression-free survival (PFS) while demonstrating an improved safety profile.
“Chondrosarcoma Pipeline Insight, 2024” report by DelveInsight outlines a comprehensive assessment of the present clinical/non-clinical development activities and growth prospects across the Chondrosarcoma Market.
The Chondrosarcoma Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers, acquisition, funding, designations, and other product-related details.
Chondrosarcoma Pipeline Analysis
The report provides insights into:
The report provides detailed insights into the emerging therapies for the treatment of Chondrosarcoma and the aggregate therapies developed by major pharma companies.
It accesses the different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of clinical development.
It outlines the key companies involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
The report evaluates the drugs that are under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
It navigates the major collaborations (company-company collaborations and company-academia collaborations), licensing agreements, financing details, data presentation by the pharma giants, and regulatory approval in the Chondrosarcoma market.
The report is built using data and information traced from the researcher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.
Analysis of Emerging Therapies by Phases
The report covers the emerging products under different phases of clinical development like –
Late-stage products (Phase III)
Mid-stage products (Phase II)
Early-stage product (Phase I)
Pre-clinical and Discovery stage candidates
Discontinued & Inactive candidates
Route of Administration
Chondrosarcoma pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
Oral
Parenteral
Intravenous
Subcutaneous
Topical
Molecule Type
Products have been categorized under various Molecule types such as
Monoclonal Antibody
Peptides
Polymer
Small molecule
Gene therapy
Learn How the Ongoing Clinical & Commercial Activities will Affect the Chondrosarcoma Therapeutic Segment @ https://www.delveinsight.com/report-store/chondrosarcoma-pipeline-insight
Chondrosarcoma Therapeutics Landscape
Several major pharma and biotech companies are developing therapies for Chondrosarcoma. Currently, Inhibrx is leading the therapeutics market with its Chondrosarcoma drug candidates in the most advanced stage of clinical development.
Emerging Chondrosarcoma Drugs
INBRX-109: Inhibrx
INBRX-109, Inhibrx’s most advanced therapeutic candidate, is designed to induce tumor-specific cell death by activating the DR5 receptor, which is involved in the apoptosis of cancer cells. DR5 is a receptor for the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), and its activation selectively eliminates damaged or neoplastic cells, while normal cells are generally more resistant to DR5-mediated cell death.
INBRX-109 is a tetravalent DR5 agonistic antibody that enhances DR5 signaling through efficient receptor clustering, leading to targeted cancer cell death. The drug is currently being tested in a Phase II trial with the potential to support regulatory approval. Inhibrx expects topline results from this pivotal trial in the second half of 2024, which could pave the way for INBRX-109’s approval for chondrosarcoma by 2025.
TIBSOVO (ivosidenib): Servier
TIBSOVO, developed by Servier, is an isocitrate dehydrogenase-1 (IDH1) inhibitor. A Phase III, multicenter, double-blind, randomized, placebo-controlled trial is currently underway to evaluate ivosidenib in patients aged 18 and older with locally advanced or metastatic conventional chondrosarcoma harboring an IDH1 mutation. This study includes both treatment-naive patients and those previously treated with a single systemic regimen, and is expected to be completed by 2031.
Key Companies in the Chondrosarcoma Therapeutic Market Include:
Inhibrx, Inc.
PharmaMar
Agios Pharmaceuticals
Iovance Biotherapeutics
Forma Therapeutics
Eli Lilly and Company
IGM Biosciences, Inc.
AnHeart Therapeutics
Roche
Salarius Pharmaceuticals
And Many Others
Chondrosarcoma Therapies Covered in the Report Include:
INBRX-109: Inhibrx
AG120: Agios Pharmaceuticals
And Many More
Request the Sample PDF to Get a Better Understanding of the Emerging Drugs and Key Companies @ https://www.delveinsight.com/sample-request/chondrosarcoma-pipeline-insight
Table of Contents
1. Report Introduction
2. Executive Summary
3. Chondrosarcoma Current Treatment Patterns
4. Chondrosarcoma – DelveInsight’s Analytical Perspective
5. Therapeutic Assessment
6. Chondrosarcoma Late Stage Products (Phase-III)
7. Chondrosarcoma Mid-Stage Products (Phase-II)
8. Chondrosarcoma Early Stage Products (Phase-I)
9. Pre-clinical Products and Discovery Stage Products
10. Inactive Products
11. Dormant Products
12. Chondrosarcoma Discontinued Products
13. Chondrosarcoma Product Profiles
14. Key Companies in the Chondrosarcoma Market
15. Key Products in the Chondrosarcoma Therapeutics Segment
16. Dormant and Discontinued Products
17. Chondrosarcoma Unmet Needs
18. Chondrosarcoma Future Perspectives
19. Chondrosarcoma Analyst Review
20. Appendix
21. Report Methodology
Download Sample PDF to Explore the Key Offerings of the Report: https://www.delveinsight.com/sample-request/chondrosarcoma-pipeline-insight
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