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The intricate mechanisms behind genetic disorders are reshaping how we understand human disease. Inborn errors of immunity (IEIs), a group of monogenic disorders, exemplify this complexity. These conditions arise from genetic defects impairing innate or adaptive immune functions, leading to heightened susceptibility to infections, autoimmunity, allergies, or malignancies. Over 450...
Researchers from the University of Leicester, working with international collaborators, have unraveled a key mechanism by which dietary cholesterol is absorbed into cells. This discovery, published in Science, promises innovative therapeutic pathways to control cholesterol uptake, potentially reducing cardiovascular disease rates globally. Cholesterol, a fatty substance in the bloodstream, is...
The global population is set to increase by nearly 2 billion in the next three decades. This growth comes with a significant demographic shift: one in six individuals in developed economies will be over 65 years old. For the food industry, this creates a pressing challenge—offering healthier, sustainable, and convenient...
