Major Depressive Disorder Clinical Trials Assessment 2024: FDA Approvals, Pipeline, Therapies, MOA, ROA and Companies by DelveInsight

Major Depressive Disorder Clinical Trials
Major Depressive Disorder companies are GH Research, Praxis Precision Medicines, AbbVie, Gedeon Richter, Intra-Cellular Therapies, Bristol-Myers Squibb, Relmada Therapeutics, SAGE Therapeutics, Janssen Research & Development, Minerva Neurosciences, Takeda, Neurocrine Biosciences, Pherin Pharmaceuticals, and others.

(Albany, USA) DelveInsight’s, “Major Depressive Disorder Pipeline Insight” report provides comprehensive insights about 75+ companies and 75+ pipeline drugs in the Major Depressive Disorder pipeline landscape. It covers the Major Depressive Disorder pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Major Depressive Disorder pipeline therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

 

Request a sample and discover the recent advances in Major Depressive Disorder Treatment Drugs @ Major Depressive Disorder Pipeline Report

 

Key Takeaways from the Major Depressive Disorder Pipeline Report

DelveInsight’s Major Depressive Disorder pipeline report depicts a robust space with 75+ active players working to develop 75+ pipeline therapies for Major Depressive Disorder treatment.
The leading companies working in the Major Depressive Disorder Market include GH Research, Praxis Precision Medicines, AbbVie, Gedeon Richter, Intra-Cellular Therapies, Bristol-Myers Squibb, Relmada Therapeutics, SAGE Therapeutics, Janssen Research & Development, Minerva Neurosciences, Takeda, Neurocrine Biosciences, Pherin Pharmaceuticals, and others.
Promising Major Depressive Disorder Pipeline Therapies in the various stages of development include Brexpiprazole, Desvenlafaxine Succinate Sustained-Release 10mg, Cariprazine, Antidepressant Therapy (ADT), and others.
On December 2023, Cybin IRL Limited announced a study of Phase 1 & 2 clinical trials for CYB003. The purpose of this study is to determine the safety and tolerability of ascending oral doses of CYB003 in healthy participants with and without major depressive disorder (MDD).
On November 2023, Neumora Therapeutics Inc. announced a study of Phase 3 clinical trials for NMRA 335140. This is a randomized, double blind, placebo controlled, multicenter study to evaluate the effects of NMRA 335140 (formerly BTRX 335140) on symptoms of depression in participants with Major Depressive Disorder (MDD). The study design consists of a Screening Period (up to 28 days), and a 6-week Treatment Period (during which participants will receive either NMRA 335140 or placebo). At the completion of the 6-week Treatment Period, participants who complete the study, provide informed consent, and meet the eligibility criteria may enter an extension study (NMRA 335140 501).
On October 2023, Neumora Therapeutics Inc. announced a study of phase 3 clinical trials for NMRA 335140. This is a randomized, double blind, placebo controlled, multicenter study to evaluate the effects of NMRA 335140 (formerly BTRX 335140) on symptoms of depression in participants with Major Depressive Disorder (MDD). The study design consists of a Screening Period (up to 28 days), and a 6-week Treatment Period (during which participants will receive either NMRA 335140 or placebo). At the completion of the 6-week Treatment Period, participants who complete the study, provide informed consent, and meet the eligibility criteria may enter an extension study (NMRA 335140 501).
On October 2023, Intra-Cellular Therapies Inc. announced a study of Phase 3 clinical trials of Lumateperone. This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, fixed-dose study in patients with a primary diagnosis of MDD according to criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) who have an inadequate response to ongoing ADT.

In the Major Depressive Disorder pipeline report, a detailed description of the drug is given which includes the mechanism of action of the drug, Major Depressive Disorder clinical trials studies, NDA approvals (if any), and product development activities comprising the technology, Major Depressive Disorder collaborations, licensing, mergers and acquisition, funding, designations and other product-related details.

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Major Depressive Disorder Overview

Major depressive disorder (MDD) is a common and serious mental health condition characterized by persistent feelings of sadness, loss of interest or pleasure in most activities, and a variety of emotional and physical problems. It affects daily functioning and can significantly impair a person’s quality of life.

Symptoms of Major depressive disorder include depressed mood, fatigue, changes in appetite and sleep patterns, difficulty concentrating, feelings of worthlessness or excessive guilt, and recurrent thoughts of death or suicide. To be diagnosed with Major depressive disorder, these symptoms must be present most of the day, nearly every day, for at least two weeks

The exact cause of Major depressive disorder is unknown, but it is believed to result from a combination of genetic, biological, environmental, and psychological factors. Neurotransmitter imbalances, hormonal changes, and stressful life events are among the contributing factors.

Major depressive disorder Diagnosis is based on clinical evaluation, patient history, and standardized assessment tools. Treatment typically involves a combination of medication, such as antidepressants, and psychotherapy, such as cognitive-behavioral therapy (CBT). Lifestyle changes, including regular exercise, a healthy diet, and adequate sleep, can also help manage symptoms.

Early intervention and consistent treatment are crucial for improving outcomes and preventing recurrence. Ongoing research aims to better understand the underlying mechanisms of Major depressive disorder and develop more effective treatments.

Find out more about Major Depressive Disorder Therapeutics Assessment @ Major Depressive Disorder Preclinical and Discovery Stage Products

Major Depressive Disorder Emerging Drugs Profile

SAGE-217: Sage Therapeutics
REL-1017: Relmada Therapeutics, Inc
Seltorexant: Minerva Sciences
SP-624: Sirtsei Pharmaceuticals, Inc.
SPL026: Small Pharma
PDC-1421: BioLite Inc

Major Depressive Disorder Pipeline Therapeutics Assessment

There are approx. 75+ key companies which are developing the Major Depressive Disorder therapies. The Major Depressive Disorder companies which have their Major Depressive Disorder drug candidates in the most advanced stage, i.e. Preregistration include SAGE Therapeutics.

DelveInsight’s Major Depressive Disorder pipeline report covers around 75+ products under different phases of clinical development like

Late stage products (Phase III)
Mid-stage products (Phase II)
Early-stage product (Phase I) along with the details of
Pre-clinical and Discovery stage candidates
Discontinued & Inactive candidates

Major Depressive Disorder pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

Oral
Subcutaneous
Intravenous
Intramuscular

Major Depressive Disorder Products have been categorized under various Molecule types such as

Specific Antibody
Peptides
Small molecule
Gene therapy

Learn more about the emerging Major Depressive Disorder Pipeline Therapies @ Major Depressive Disorder Clinical Trials Assessment

Scope of the Major Depressive Disorder Pipeline Report

Coverage- Global
Major Depressive Disorder Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
Major Depressive Disorder Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III
Major Depressive Disorder Companies- GH Research, Praxis Precision Medicines, AbbVie, Gedeon Richter, Intra-Cellular Therapies, Bristol-Myers Squibb, Relmada Therapeutics, SAGE Therapeutics, Janssen Research & Development, Minerva Neurosciences, Takeda, Neurocrine Biosciences, Pherin Pharmaceuticals, and others.
Major Depressive Disorder Pipeline Therapies- Brexpiprazole, Desvenlafaxine Succinate Sustained-Release 10mg, Cariprazine, Antidepressant Therapy (ADT), and others.

Dive deep into rich insights for new drugs for Major Depressive Disorder Treatment, Visit @ Major Depressive Disorder Treatment Market

Table of Content

Introduction
Executive Summary
Major Depressive Disorder: Overview
Pipeline Therapeutics
Therapeutic Assessment
Major Depressive Disorder – DelveInsight’s Analytical Perspective
Late Stage Products (Preregistration)
SAGE-217: Sage Therapeutics
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
SP-624: Sirtsei Pharmaceuticals, Inc.
Drug profiles in the detailed report…..
Early Stage Products (Phase I/II)
SPL026: Small Pharma
Drug profiles in the detailed report…..
Preclinical Stage Products
Drug Name: Company name
Drug profiles in the detailed report…..
Inactive Products
Major Depressive Disorder Key Companies
Major Depressive Disorder Key Products
Major Depressive Disorder- Unmet Needs
Major Depressive Disorder- Market Drivers and Barriers
Major Depressive Disorder- Future Perspectives and Conclusion
Major Depressive Disorder Analyst Views
Major Depressive Disorder Key Companies
Appendix

About DelveInsight

DelveInsight is a leading Life Science market research and business consulting company recognized for its off-the-shelf syndicated market research reports and customized solutions to firms in the healthcare sector.

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